Nicholas P. Lang, M.D. is the Chief of Staff at CAVHS and a Professor in the Department of Surgery, Division of Surgical Oncology, at the Arkansas Cancer Research Center at UAMS.  Dr. Lang’s research is focused on identifying the genetic basis for individual differences in carcinogen metabolism in conjunction with epidemiological studies that measure carcinogen exposure from dietary and environmental sources.  Dr. Lang has had a long-standing interest in understanding the basic mechanisms of cancer in the elderly, with particular emphasis on prostate, breast and colorectal cancer.

Selected Publications:

Nowell S, Sweeney C, Hammonds G, Kadlubar FF, Lang NP. CYP2A6 activity determined by caffeine phenotyping: association with colorectal cancer risk. Ca Epidemiol Biomark and Prev. 2002;11:377-383.

Sweeney C, Coles B, Nowell SA, Lang NP, Kadlubar FF. Novel markers of susceptibility to carcinogens in diet: associations with colorectal cancer. Toxicology. 2002;181-182:83-87.

Nowell S, Coles B, Sinha R, MacLeod S, Ratnasinghe L, Stotts C, Kadlubar FF, Ambrosone CB, Lang NP. Analysis of total meat intake and exposure to individual heterocyclic amines in a case-control study of colorectal cancer: contribution of metabolic variation to risk. Mutation Research 2002;506-507C:175-185.

Anderson KE, Sinha R, Kulldorff M, Gross M, Lang NP, Barber C, Harnack L, DiMagno E, Bliss R, Kadlubar FF. Meat intake and cooking techniques: Associations with pancreatic cancer. Mutation Research 2002;506-507C:225-231.

Nowell S, Sweeney C, Winters M, Stone A, Lang NP, Hutchins LF, Kadlubar FF, Ambrosone CB. Association between sulfotransferase 1A1 genotype and survival of breast cancer patients receiving tamoxifen therapy. J Natl Ca Inst 2002;94:1635-1640.