Sudhir Shah, M.D., M.B.B.S. is the Director of Nephrology at UAMS. Major research projects in the Department of Nephrology include studies involving mechanism and control of ion absorption by the thick ascending limb of Henle’s loop; the role of phosopholipase A2 in acute ischemic injury to the kidney; the role of reactive oxygen species in real injury, utilitizing freshly isolated glomeruli and cultured ells, and in vivo models of glomerular disease and acute renal failure. Clinical studies include the use of erythropoietin in chronic dialysis patients, insulin levels in black hypertensives, the role of ACE inhibitors in the management of hypertension associated with chronic renal insufficiency, and innovative techniques in renal replacement therapies to include peritoneal dialysis, hemodialysis, hemofiltration, and intensive care nephrology.
Shah SV, Walker PD, Ueda N, Nath KA: Reactive oxygen metabolites in toxic acute renal failure. In Current Nephrology, Vol 18, Gonick H, editor, Mosby Year Book, 1994.
Shah SV: The role of reactive oxygen metabolites in glomerular disease. In Annual Review of Physiology, Vol. 57, Hoffman JF, editor, Annual Reviews Inc., 1995.
Baliga R, Ueda N, Walker PD, Shah SV: Oxidant mechanisms in toxic acute renal failure. Am J Kid Dis, 1997. 29(3):465-477.
Baliga R, Ueda N, Walker PD, Shah SV: Oxidant mechanisms in toxic acute renal failure. Invited: Drug Metabolism Reviews, 1999 (Nov). 31 (4): 971-979.
Shah SV. Role of iron in progressive renal disease. Am J Kidney Dis, 2001 (January) 37. (1, Suppl 2): S30-S33.